• A-PVP

    Effects of MDPV, α-PVP, cocaine, and amphetamine on inhibition of [3H] transmitter uptake at dopamine (DAT), norepinephrine (NET) and serotonin (SERT) transporters[psycho wiki]
    Compound DAT (nM) NET (nM) SERT (nM) DAT/SERT ratio
    a-PVP 12.8 ± 1.2 14.2 ± 1.2 >10,000 >781
    MDPV 4.1 ± 0.6 25.9 ± 5.6 3305 ± 485 806
    Cocaine 211 ± 19 292 ± 34 313 ± 17 1.5
    Amphetamine 93 ± 17 67 ± 16 3418 ± 314 37
     18,00 20,00

    A-PVP

     18,00 20,00

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